Choreoathetoid Movements in a Type 2 Diabetic Patient Following Initiation of Oral Hypoglycemics: A Case Study

  • Jadhav V Tanya 2nd MBBS student, Dr. Chandramma Dayananda Sagar Institute of Medical Education and Research, Dayananda Sagar University, Harohalli, Kanakapura Taluk, Ramanagara District, Karnataka, India
  • V. S. Nagashree Assistant Professor, Neurology Department, Dr. Chandramma Dayananda Sagar Institute of Medical Education and Research, Dayananda Sagar University, Harohalli, Kanakapura Taluk, Ramanagara District, Karnataka, India
  • Betsy Mathew Professor, General Medicine Department, Dr. Chandramma Dayananda Sagar Institute of Medical Education and Research, Dayananda Sagar University, Harohalli, Kanakapura Taluk, Ramanagara District, Karnataka, India
  • V. Karthik Senior Resident, Pharmacology Department, Dr. Chandramma Dayananda Sagar Institute of Medical Education and Research, Dayananda Sagar University, Harohalli, Kanakapura Taluk, Ramanagara District, Karnataka, India
  • Shiva Murthy Nanjundappa Dr Chandramma Dayananda Sagar Institute of Medical Education and Research (CDSIMER), Devarakaggalahalli, Harohalli, Ramanagara District, Karnataka, India
Keywords: Choreoathetoid Movements, Antidiabetic Drugs, Type II Diabetes, Pharmacovigilance

Abstract

Introduction: Choreoathetoid movements, characterized by a combination of rapid, jerky, and sustained muscle contractions, can be associated with various neurological conditions and medication side effects. This case report describes a 68-year-old male with newly diagnosed type 2 diabetes mellitus who developed bilateral choreoathetoid movements following the initiation of oral hypoglycemic therapy.

Case Presentation: A 68-year-old male presented with involuntary movements in all limbs after starting treatment with Vildagliptin and Metformin. Neurological evaluation revealed bilateral choreoathetoid movements and oral dyskinesia. Imaging studies showed infarcts in the right basal ganglia.

Discussion: This case highlights the need to consider adverse drug reactions and diabetes-related complications when assessing new-onset choreoathetoid movements. The role of Vildagliptin and Metformin in this presentation remains inconclusive, necessitating further investigation.

Conclusion: The patient’s choreoathetoid movements could be attributed to medication side effects, diabetes complications, or both. Careful evaluation is essential for accurate diagnosis and management.

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References

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Published
2025-09-01
How to Cite
1.
Jadhav TV, V.S N, Mathew B, V K, Nanjundappa SM. Choreoathetoid Movements in a Type 2 Diabetic Patient Following Initiation of Oral Hypoglycemics: A Case Study. jpadr [Internet]. 2025Sep.1 [cited 2025Oct.9];6(3):12-4. Available from: https://jpadr.com/index.php/jpadr/article/view/195