Drug development hit by war
Abstract
Introduction: Drug development is the process by which academic, pharmaceutical, or government laboratories identify or screen new chemical entities to find potentially active pharmacological compounds and bring them to the market. This process is undoubtedly the heart and soul of modern medicine. War is an incidental condition that can disrupt the drug development pipeline and clinical research. During the current Russia-Ukraine war, multiple sanctions are being imposed on Russia which is disrupting the supply chain and slowing down the process of drug development.
Objective: This review was done to understand how war and international conflicts affect the global drug development process.
Methods: Information was obtained by reviewing the data from previously published news material. We used PubMed, Google Scholar, Web of Science, Medline, and Embase as our search engines and keywords like (Ukraine, Russia, clinical trial, pharmaceutical industry, war, and drug development). In total, we reviewed 74 articles, and the obtained information was interpreted, compiled, evaluated, reassembled, deconstructed and conclusions were reached.
Conclusion: In the past despite multiple wars, mankind has not learned from their past mistakes. The pharmaceutical industry should form mitigation plans so that in the time of crisis other options are available for drug discovery and clinical research.
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