Drug development hit by war

  • Hara Prasad Mishra 1.University College of Medical Sciences, University of Delhi, Delhi, India 2. All India Institute of Medical Sciences , Delhi , India 3.National Law School of India University , Bangalore , India
  • Ayush Goel University College of Medical Sciences, University of Delhi, Delhi, India
  • Sahil Kumar HOD Department Of Pharmacology , ESIC Dental college , Rohini, Delhi , India
  • Mihir Chauhan Vallabhbhai Patel Chest Institute , University of Delhi, Delhi, India
  • Mrinal Patnaik All India Institute of Medical Sciences , Bhopal , India
  • Imaad Rehman University College of Medical Sciences, University of Delhi, Delhi, India
Keywords: Ukraine, Russia, Clinical trial, Pharmaceutical industry, War, Drug development

Abstract

Introduction: Drug development is the process by which academic, pharmaceutical, or government laboratories identify or screen new chemical entities to find potentially active pharmacological compounds and bring them to the market. This process is undoubtedly the heart and soul of modern medicine. War is an incidental condition that can disrupt the drug development pipeline and clinical research. During the current Russia-Ukraine war, multiple sanctions are being imposed on Russia which is disrupting the supply chain and slowing down the process of drug development.

Objective: This review was done to understand how war and international conflicts affect the global drug development process.

Methods: Information was obtained by reviewing the data from previously published news material. We used PubMed, Google Scholar, Web of Science, Medline, and Embase as our search engines and keywords like (Ukraine, Russia, clinical trial, pharmaceutical industry, war, and drug development). In total, we reviewed 74 articles, and the obtained information was interpreted, compiled, evaluated, reassembled, deconstructed and conclusions were reached.

Conclusion: In the past despite multiple wars, mankind has not learned from their past mistakes. The pharmaceutical industry should form mitigation plans so that in the time of crisis other options are available for drug discovery and clinical research.

References

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Published
2022-06-01
How to Cite
1.
Mishra HP, Goel A, Sahil Kumar, Chauhan M, Patnaik M, Rehman I. Drug development hit by war . jpadr [Internet]. 2022Jun.1 [cited 2022Nov.26];3(2):11-5. Available from: https://jpadr.com/index.php/jpadr/article/view/74