Knowledge, attitude and practice towards adverse drug events reporting among graduating health science students of college of health sciences, Addis Ababa University, Ethiopia
Introduction: The knowledge, attitude, and practice of the health sciences students are crucial for their future monitoring and reporting of adverse drug events as professional responsibility.
Aim: To describe the knowledge, attitude, and practice of graduating medicine and pharmacy students at the College of Health Sciences, Addis Ababa, Ethiopia
Method: This study was based on a cross-sectional study design. Data were collected through a structured and pilot-tested questionnaire. The data was entered and analyzed using SPSS version 20. The descriptive statistics such as frequency, mean, standard deviation, percentages computed, and the association between variables were conducted using Chi-square. The p-value of < 0.05 was taken as statistically significant.
Result: A total of 140 students were included in this study. The majority of the participants were medicine students 82 (58.6 %) and males 84 (60 %). Most of the respondents, 106 (75.7 %) knew the ADE reporting system, and 126 (98.6 %) drug safety monitoring is important. However, about half of the students 65 (46.4 %) were not aware of the national ADE reporting system. During clerkships 57 (40.7 %) participants encountered at least once ADE, but only 23 (16.4%) of them had reported it. Graduating pharmacy students have better knowledge on “pharmacovigilance” (84.5 % Vs 43.9 %, p < 0.001) but medicine students were better at reporting the encountered ADE (22.0 % Vs 8.6 %, p = 0.04).
Conclusion: The graduating medical interns and pharmacy students have a positive attitude towards ADEs. However, they have a low level of knowledge and practice about voluntary adverse drug events reporting.
Adisa, R., & Omitogun, T. I. (2019). Awareness, knowledge, attitude and practice of adverse drug reaction reporting among health workers and patients in selected primary healthcare centres in Ibadan, southwestern Nigeria. BMC health services research, 19(1), 926.
Arabyat, R.M., Sanchez Martinez, A., Nusair, M.B. (2020). Adverse drug event reporting by pharmacists: a systematic literature review. Journal of pharmaceutical health services research 11(1), 5–23.
Becker, S., 2004. Contemporary view of medication-related harm. a New paradigm.
DACA, 2009. Report on the assessment health care provider’s knowledge, attitude and practice on adverse drug reaction reporting and its monitoring. Addis ababa, Ethiopia.
Davies, E. C., Green, C. F., Taylor, S., Williamson, P. R., Mottram, D. R., & Pirmohamed, M. (2009). Adverse drug reactions in hospital in-patients: a prospective analysis of 3695 patient-episodes. PloS one, 4(2), e4439.
EFDA, 2020. Ethiopian Food and Drug Authority Pharmacovigilance Directive September 2020.
Ermias, A., Gurmesa, G., Mesfin, M., Mengistu, A. (2011). Adverse drug reaction monitoring in Ethiopia: Analysis of case reports, 2002-2007. Ethiopian Journal of Health Development. 25(2), 168–173.
FMHACA, 2014. Guideline for Adverse Drug Events Monitoring ( Pharmacovigilance ), third. ed. Addis ababa, Ethiopia.
Gidey, K., Seifu, M., Hailu, B. Y., Asgedom, S. W., & Niriayo, Y. L. (2020). Healthcare professionals knowledge, attitude and practice of adverse drug reactions reporting in Ethiopia: a cross-sectional study. BMJ open, 10(2), e034553.
Hindoliya, M., Chitapure, F. (2019). A study on the knowledge, attitude and practice on adverse drug reactions and pharmacovigilance among post graduate residents in Gandhi Medical College, Bhopal. International Journal of Basic & Clinical Pharmacology, 8(9), 2108
John, L. J., Arifulla, M., Cheriathu, J. J., & Sreedharan, J. (2012). Reporting of adverse drug reactions: an exploratory study among nurses in a teaching hospital, Ajman, United Arab Emirates. Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 20(1), 44.
Kefale, A., Tefera, B., & Biru, T. (2017). Knowledge, attitude and practice of healthcare professionals towards adverse drug reaction reporting at inpatient wards of tertiary hospital, ethiopia. Journal of Drug Delivery and Therapeutics, 7(4), 97-102.
Lopez-Gonzalez, E., Herdeiro, M. T., & Figueiras, A. (2009). Determinants of under-reporting of adverse drug reactions: a systematic review. Drug safety, 32(1), 19–31.
Mulatu, W.N., Worku, A. (2014). Pharmacovigilance Assessment of Knowledge , Attitude and Practice of Health Professionals towards Adverse Drug Reaction Reporting and Factors Associated with Reporting. J Pharmacovigil. 2, 1–7.
Nadew, S. S., Beyene, K. G., & Beza, S. W. (2020). Adverse drug reaction reporting practice and associated factors among medical doctors in government hospitals in Addis Ababa, Ethiopia. PloS one, 15(1), e0227712.
Nisa, Z. U., Zafar, A., & Sher, F. (2018). Assessment of knowledge, attitude and practice of adverse drug reaction reporting among healthcare professionals in secondary and tertiary hospitals in the capital of Pakistan. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 26(4), 453–461.
Schatz, B.S.N., Weber, R.J., 2015. Adverse Drug Reactions. PSAP.
Siddeshwara, M.G., Santoshkumar, J., Vardhamane, S.., (2016). Knowledge, Attitude and Practice of Adverse Drug Reactions Reporting Among Healthcare Professionals. International Journal of Pharmacological Research 6(1), 18–22.
Suyagh, M., Farah, D., & Abu Farha, R. (2015). Pharmacist's knowledge, practice and attitudes toward pharmacovigilance and adverse drug reactions reporting process. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 23(2), 147–153.
Upadhyaya, H. B., Vora, M. B., Nagar, J. G., & Patel, P. B. (2015). Knowledge, attitude and practices toward pharmacovigilance and adverse drug reactions in postgraduate students of Tertiary Care Hospital in Gujarat. Journal of advanced pharmaceutical technology & research, 6(1), 29–34.
WHO, 2004. Pharmacovigilance: ensuring the safe use of medicines. World Health 1–6.
Zewde, G.T. (2020). Knowledge, Attitude and Practice of Health Care Professionals Towards Adverse Drug Reaction Reporting in Public Hospitals of Harar Town, Eastern, Ethiopia. Biomedical journal of scientific and technical. research, 32(2), 24793–24799.
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