Medical treatment options available for mucormycosis

Review Article

  • Shiva Murthy Nanjundappa Dr Chandramma Dayananda Sagar Institute of Medical Education and Research (CDSIMER), Devarakaggalahalli, Harohalli, Ramanagara District, Karnataka, India
Keywords: Mucormycosis, Medical Treatment

Abstract

Introduction: Mucormycosis is known as a rapidly progressive and invasive lethal fungal infection. The predisposing factors known to potentiate this fungal infection are diabetes mellitus, primary or secondary immunodeficiency, etc. The clinical presentation of these cases may vary from involvement of localized skin infection to disseminated systemic infection.

Methods: In this article, an attempt was made to review the therapeutic guidelines released by European Committee for Antimicrobial Susceptibility Testing (EUCAST) and Clinical and Laboratory Standards Institute (CLSI).

Results: In addition to this, efforts were made to briefly review the evidence available on various formulations of accepted treatment methods including Amphotericin B (AmB), Posaconazole (PSZ), and Isavuconazole (ISZ), and other newer anti-fungal agents such as Voriconazole (VCZ), Echinocandins, etc.  

Conclusions: An attempt was also made to discuss the various drugs that can be used as a single agent or combinations considered to be synergistically active and beneficial for the treatment/ prophylaxis of Mucormycosis.

Author Biography

Shiva Murthy Nanjundappa, Dr Chandramma Dayananda Sagar Institute of Medical Education and Research (CDSIMER), Devarakaggalahalli, Harohalli, Ramanagara District, Karnataka, India

Department of Pharmacology, Associate Professor

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Published
2021-12-01
How to Cite
1.
Nanjundappa SM. Medical treatment options available for mucormycosis . jpadr [Internet]. 2021Dec.1 [cited 2022Jan.22];2(4):14-1. Available from: https://jpadr.com/index.php/jpadr/article/view/49