Prescription audit a tool to determine the effects of antibiotics in the pediatric inpatient department of a tertiary teaching care hospital in Punjab

Research Article

  • Monika Kapoor I.S.F College of Pharmacy, Moga, Punjab, India https://orcid.org/0000-0001-6277-4296
  • Jagminder Kaur Bajaj Punjab Institute of Medical Science, Jalandhar, Punjab, India.
  • Shalini Salwan Punjab Institute of Medical Science, Jalandhar, Punjab, India
Keywords: Infants and children, antimicrobials, audit, Inpatient Department, Infection, Prescription pattern

Abstract

Health care professionals dealing with pediatric patients face a lot of challenges and pass through hurdles during their daily practice of medicines owing to the scarcity of suitable drugs and other facilities. A fundamental part of the antibiotic prescription is inappropriate due to errors in the selection of appropriate antibiotics, dose, duration, route of administration, and frequency for treatment. Medication use evaluation and audits are an integral part of evaluating whether the drugs are being utilized appropriately considering the social, economic, and medical points. The main objective of this study was to do an antibiotic audit to analyze the prescribing pattern in the in-patient department of pediatrics of the hospital. A prospective observational study was conducted in the inpatient pediatrics department of Punjab Institute of Medical Science and Hospital, Jalandhar. The study was conducted on a total of 150 hospitalized children and infants for a period of two months from February 1, 2020, to March 30, 2020. The analysis of 150 prescriptions was done using IBM SPSS software version 24 and statistical analysis was done. Antibiotic usage was expressed in percentile and the duration of treatment was expressed. Aminoglycosides (Amikacin) were the top most used class of antibiotics followed by cephalosporin. Among cephalosporins, the third generation ceftriaxone, and cefoperazone were found to be mostly used. Accordingly, health care professionals must keep a clear understanding of the need for microbiological diagnosis, antibiotics usage, and make good judgment in clinical situations. Regular antibiotic audits and staff education must be implemented.

Author Biographies

Monika Kapoor, I.S.F College of Pharmacy, Moga, Punjab, India

Department of Pharmacy Practice

Jagminder Kaur Bajaj, Punjab Institute of Medical Science, Jalandhar, Punjab, India.

Department of Pharmacology

Shalini Salwan, Punjab Institute of Medical Science, Jalandhar, Punjab, India

Department of Pharmacology

References

Baidya S, Hazra A, Datta S, and Das AK. A study of antimicrobial use in children admitted to pediatric medicine ward of a tertiary care hospital. Indian journal of pharmacology, 2017; 49(1): 10-15.
Choudhury DK, and Bezbaruah BK. Antibiotic prescriptions pattern in paediatric in-patient department gauhati medical college and hospital, Guwahati. Journal of Applied pharmaceutical science, 2013; 3(8): 144-148.
Dramowski, A. Paediatric antimicrobial use at a South African hospital. International Journal of Infectious Diseases, 2018; 74: 16-23.
Fahimzad A, Eydian Z, Karimi A, Shiva F, Sayyahfar S, Kahbazi M, et al., Surveillance of antibiotic consumption point prevalence survey 2014: Antimicrobial prescribing in pediatrics wards of 16 Iranian hospitals. Archives of Iranian medicine, 2016; 19(3): 204-209.
Kolar JV, and Kadakova E. Prescription of antimicrobial drugs to hospitalized children. Annals of Pharmacotherapy, 1993; 27(7-8): 974-977.
Koopmans LR, Finlayson H, Whitelaw A, Decloedt EH, and Dramowski A. Paediatric antimicrobial use at a South African hospital. International Journal of Infectious Diseases, 2018; 74: 16-23.
Marr JJ. Guidelines for improving the use of antimicrobial agents in hospitals: a statement by the Infectious Disease Society of America. J Infect Dis. 1988; 157: 869-76.
Palikhe, N. Prescribing pattern of antibiotics in pediatric hospital of Kathmandu valley. Journal of Nepal Health research council. 2004; 2(1): 6-12.
Principi N. Control of antibiotic therapy in paediatric patients. Developmental pharmacology and therapeutics, 1981; 2:145-55.
Priyadharsini R, Surendiran A, Adithan C, Sreenivasan S, Sahoo FK. A study of adverse drug reactions in pediatric patients. Journal of pharmacology & pharmacotherapeutics, 2011; 2(4): 277-280.
Sanz EJ, Bergman U, and Dahlstrom M. Paediatric drug prescribing. a comparison of Tenerife (Canary Islands, Spain) and Sweden. European journal of clinical pharmacology, 1989; 37(1): 65-68.
Schollenberg E, and Albritton WL. Antibiotic misuse in a pediatric teaching hospital. Canadian Medical Association Journal, 1980; 122(1): 49-52.
Smith MJ, Gerber JS, and Hersh AL. Inpatient antimicrobial stewardship in pediatrics: a systematic review. Journal of the Pediatric Infectious Diseases Society, 2015; 4(4): e127-e135.
Summers RS, and Summers B. Drug prescribing in paediatrics at a teaching hospital serving a developing community. Annals of tropical paediatrics, 1989; 6(2): 129-133.
Woldu MA, Suleman S, Workneh N, and Berhane H Retrospective study of the pattern of antibiotic use in Hawassa University referral hospital pediatric ward, Southern Ethiopia. Journal of Applied Pharmaceutical Science, 2013; 3(2): 93-98.
Published
2021-06-06
How to Cite
1.
Monika Kapoor, Jagminder Kaur Bajaj, Shalini Salwan. Prescription audit a tool to determine the effects of antibiotics in the pediatric inpatient department of a tertiary teaching care hospital in Punjab. jpadr [Internet]. 2021Jun.6 [cited 2021Oct.16];2(1):33-7. Available from: https://jpadr.com/index.php/jpadr/article/view/25