A rare case of accelerated gingival overgrowth with high dose amlodipine therapy

  • Rakesh B M Vydehi Institute of Medical Sciences and Research Centre (VIMS&RC), Bangalore, Karnataka, India
  • Sahithi Sharma Vydehi Institute of Medical Sciences and Research Centre (VIMS&RC), Bangalore, Karnataka, India https://orcid.org/0000-0003-4095-3714
  • Chandana K H Vydehi Institute of Medical Sciences and Research Centre (VIMS&RC), Bangalore, Karnataka, India
Keywords: Hypertension, calcium channel blockers, drug-induced gingival hyperplasia, adverse drug reaction

Abstract

Introduction: Gingival overgrowth represents an over-exuberant response to a variety of local and systemic conditions. Certain anticonvulsants, immunosuppressive drugs, and a number of calcium channel blockers have been shown to produce similar gingival overgrowth in susceptible patients.

Case report: We report a case of accelerated drug-induced gingival overgrowth in a 60-year-old hypertensive patient taking amlodipine at a dose of 10 mg.

Conclusions: Among the calcium channel blockers, nifedipine is most frequently associated with gingival overgrowth.  Whereas, there is limited evidence of amlodipine-induced gingival hyperplasia.

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Author Biographies

Rakesh B M, Vydehi Institute of Medical Sciences and Research Centre (VIMS&RC), Bangalore, Karnataka, India

Department of General Medicine

Sahithi Sharma, Vydehi Institute of Medical Sciences and Research Centre (VIMS&RC), Bangalore, Karnataka, India

Department of General Medicine

Chandana K H, Vydehi Institute of Medical Sciences and Research Centre (VIMS&RC), Bangalore, Karnataka, India

Department of General Medicine

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Published
2021-03-01
How to Cite
1.
Rakesh B M, Sahithi Sharma, Chandana K H. A rare case of accelerated gingival overgrowth with high dose amlodipine therapy. jpadr [Internet]. 2021Mar.1 [cited 2025Jan.22];2(1):39-1. Available from: https://jpadr.com/index.php/jpadr/article/view/20