A rare case of accelerated gingival overgrowth with high dose amlodipine therapy

Case Study

  • Rakesh B M Vydehi Institute of Medical Sciences and Research Centre (VIMS&RC), Bangalore, Karnataka, India
  • Sahithi Sharma Vydehi Institute of Medical Sciences and Research Centre (VIMS&RC), Bangalore, Karnataka, India https://orcid.org/0000-0003-4095-3714
  • Chandana K H Vydehi Institute of Medical Sciences and Research Centre (VIMS&RC), Bangalore, Karnataka, India
Keywords: Hypertension, calcium channel blockers, drug-induced gingival hyperplasia, adverse drug reaction

Abstract

Gingival overgrowth represents an over-exuberant response to a variety of local and systemic conditions. Certain anticonvulsants, immunosuppressive drugs, and a number of calcium channel blockers have been shown to produce similar gingival overgrowth in susceptible patients. Among the calcium channel blockers, nifedipine is most frequently associated with gingival overgrowth.  Whereas, there is limited evidence of amlodipine-induced gingival hyperplasia. We report a case of accelerated drug-induced gingival overgrowth in a 60-year-old hypertensive patient taking amlodipine at a dose of 10 mg.

Author Biographies

Rakesh B M, Vydehi Institute of Medical Sciences and Research Centre (VIMS&RC), Bangalore, Karnataka, India

Department of General Medicine

Sahithi Sharma, Vydehi Institute of Medical Sciences and Research Centre (VIMS&RC), Bangalore, Karnataka, India

Department of General Medicine

Chandana K H, Vydehi Institute of Medical Sciences and Research Centre (VIMS&RC), Bangalore, Karnataka, India

Department of General Medicine

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Published
2021-03-01
How to Cite
1.
Rakesh B M, Sahithi Sharma, Chandana K H. A rare case of accelerated gingival overgrowth with high dose amlodipine therapy. jpadr [Internet]. 2021Mar.1 [cited 2021Oct.16];2(1):15-7. Available from: https://jpadr.com/index.php/jpadr/article/view/20