Ecopharmacovigilance: Perspectives, concepts, applications, and relationships in modern context

Review Article

  • Prachi Khamkar University of Mumbai, Mumbai 400020, Maharashtra, India
  • Debarshi Kar Mahapatra Dadasaheb Balpande College of Pharmacy, Nagpur 440037, Maharashtra, India
  • Atul Kadam Shree Santakrupa College of Pharmacy, Ghogaon, Shivaji University, Kolhapur 416012, Maharashtra
Keywords: Ecopharmacovigillance, Pharmacovigilance, Pharmaceuticals, Waste, Environmental, removal


Environmental scientists have made great strides to regulate pharmaceutical waste. However, the monitoring of emerged environmental problems induced by drugs should attract further interest of pharmacy and pharmacovigilance scientists. Ecopharmacovigilance (EPV) as a kind of pharmacovigilance for the atmosphere is widely recognized as essential to minimize the environmental impact of pharmaceutical toxins. In efforts to answer the environmental issues created by medications, the constructive involvement of the pharmaceutical sector is essential. In a prioritized basis, EPV can target individual pharmaceuticals. For EPV deployment targeting pharmaceutical contamination, certain advice and management practice solutions are recommended. On administration certain drugs are metabolized throughout the bloodstream, being inert or becoming converted to metabolites, whereas others are excreted in the urine or liver and excreted in the sewage. The substances that are released into drainage can be processed into a number of chemicals by a sewage treatment process. The involvement of different drugs and their components has been found in the marine world, with the aquatic environment being the most researched to-date. Nanostructure materials have been around for a long time, and its interactions with biological processes have been discussed in various applications to enhance the understanding and importance of environmental and health effects. In order to regulate pharmaceutical residues in effluents, Technologies for sewage water management should be applied.  In particular, the presence of pharmacy including pharmacovigilance professionals is also important for enhancing multidisciplinary collaboration.

Author Biographies

Prachi Khamkar, University of Mumbai, Mumbai 400020, Maharashtra, India

Department of Pharmaceutics

Debarshi Kar Mahapatra, Dadasaheb Balpande College of Pharmacy, Nagpur 440037, Maharashtra, India

Department of Pharmaceutical Chemistry

Atul Kadam, Shree Santakrupa College of Pharmacy, Ghogaon, Shivaji University, Kolhapur 416012, Maharashtra

Department of Pharmaceutics


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How to Cite
Prachi Khamkar, Debarshi Kar Mahapatra, Atul Kadam. Ecopharmacovigilance: Perspectives, concepts, applications, and relationships in modern context. jpadr [Internet]. 2021Jun.6 [cited 2021Oct.16];2(1):9-14. Available from: