Vitamin K1 injection induced localized scleroderma like lesion in pregnancy: A case report
Abstract
Cutaneous reaction due to Vitamin K1 (Phytomenadione) injection can present as hypersensitivity reaction at the injection site with morphea like lesion that can be deep seated, involving the dermis & subcutaneous tissue, several days or weeks after injection of vitamin K1. Texier Disease,which is a scleroderma like lesion secondary to vitamin K1 injection is one of the rarely encountered & reported condition.
Localised scleroderma is a rare autoimmune disorder characterized by fibrosis of the skin and subcutaneous tissues. Although its etiology is not fully understood, several factors including environmental triggers and genetic predisposition have been implicated.
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References
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