Oxytocin induced itching in a 37 week primigravida with meconium stained liquor

  • Disha Sai M Chandavar Dr Chandramma Dayananda Sagar Institute of Medical Education and Research (CDSIMER), Devarakaggalahalli, Harohalli, Ramanagara District, Karnataka, India
  • Shiva Murthy Nanjundappa Dr Chandramma Dayananda Sagar Institute of Medical Education and Research (CDSIMER), Devarakaggalahalli, Harohalli, Ramanagara District, Karnataka, India
  • Reddy P Senior resident , Obstetrics and Gynaecology Department, Dr Chandramma Dayananda Sagar Institute of Medical Education and Research (CDSIMER), Devarakaggalahalli, Harohalli, Ramanagara District, Karnataka, India
  • Prasad N N Professor and Head of the Department, Obstetrics and Gynaecology Department, Dr Chandramma Dayananda Sagar Institute of Medical Education and Research (CDSIMER), Devarakaggalahalli, Harohalli, Ramanagara District, Karnataka, India
Keywords: Adverse drug reaction, Oxytocin, Induction of Labor, Meconium Stained Liquor

Abstract

Introduction: Oxytocin is the most frequently used medication for labour augmentation in obstetrics. One of the known benefits of its use is the improvement of uterine contractions. An injectable form of oxytocin is administered intravenously as an infusion.  Adverse drug reactions at this stage may distress the baby and worsen the outcome of the pregnancy.

Case details: A 19-year-old female with a history of nine months gestation presented in labour.  She was administered oxytocin infusion in ringer lactate to augment labor. She developed itching all over her body and was immediately administered Inj. hydrocortisone intravenously. As the foetus was in distress, she was taken for an emergency lower segment cesarean section (LSCS).

Conclusion: The administration of IV oxytocin was considered the possible cause of the development of rashes in this case. We suggest adopting preventive strategies to avoid ADRs in emergencies to avoid deleterious consequences. The preventive strategies may include screening in the antenatal period for previous history of sensitivity to oxytocin, latex, etc. In addition, other strategies are discussed in this article.

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Author Biographies

Disha Sai M Chandavar, Dr Chandramma Dayananda Sagar Institute of Medical Education and Research (CDSIMER), Devarakaggalahalli, Harohalli, Ramanagara District, Karnataka, India

Second year MBBS Student

Shiva Murthy Nanjundappa, Dr Chandramma Dayananda Sagar Institute of Medical Education and Research (CDSIMER), Devarakaggalahalli, Harohalli, Ramanagara District, Karnataka, India

Associate Professor, Pharmacology Department

Reddy P, Senior resident , Obstetrics and Gynaecology Department, Dr Chandramma Dayananda Sagar Institute of Medical Education and Research (CDSIMER), Devarakaggalahalli, Harohalli, Ramanagara District, Karnataka, India

Senior resident , Obstetrics and Gynaecology Department, Dr Chandramma Dayananda Sagar Institute of Medical Education and Research (CDSIMER), Devarakaggalahalli, Harohalli, Ramanagara District, Karnataka, India

Prasad N N, Professor and Head of the Department, Obstetrics and Gynaecology Department, Dr Chandramma Dayananda Sagar Institute of Medical Education and Research (CDSIMER), Devarakaggalahalli, Harohalli, Ramanagara District, Karnataka, India

Professor and Head of the Department, Obstetrics and Gynaecology Department, Dr Chandramma Dayananda Sagar Institute of Medical Education and Research (CDSIMER), Devarakaggalahalli, Harohalli, Ramanagara District, Karnataka, India

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Published
2023-03-01
How to Cite
1.
Chandavar DSM, Nanjundappa SM, Reddy DP, N DNP. Oxytocin induced itching in a 37 week primigravida with meconium stained liquor . jpadr [Internet]. 2023Mar.1 [cited 2024Feb.21];4(1):25-8. Available from: https://jpadr.com/index.php/jpadr/article/view/116