Drug related problems on anti-platelets and anti-coagulants in stroke

  • Mounika Thogaru St. Peter's Institute of Pharmaceutical Sciences, Vidya Nagar, Hanamkonda, Warangal, Telangana, India
Keywords: Heparin, aspirin, clopidogrel, stroke, drug related problems, drug interactions

Abstract

Introduction: Antiplatelet agents prevent platelets from dumping and prevent clots from forming and growing. Anticoagulants slow down clotting thereby reducing fibrin formation and preventing clots. Drug-related problems are a major concern in the view of physical, psychological, and economic burden to patients.

Objectives: The aim of the research work is to access, evaluate and monitor the drug-related problems on antiplatelet and anticoagulants in stroke patients. 

Methods: In this study 300 numbers of patients were screened including both males and females of all age groups in a super specialty hospital.

Results: The number of ADRs was found to be predominantly associated with a male as compared to females as well as most ADRs were reported for patients with cardiac stroke as compared to ischemic stroke and hemorrhagic stroke.

Conclusions: Low molecular weight heparins, aspirin, clopidogrel drugs resulted in various adverse drug reactions. Mostly 114 cases of ADR were due to drug-drug interactions followed by drug-food interactions and drug ethanol interactions as was concluded from the study.

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Author Biography

Mounika Thogaru, St. Peter's Institute of Pharmaceutical Sciences, Vidya Nagar, Hanamkonda, Warangal, Telangana, India

Department of Applied Sciences

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Published
2020-09-01
How to Cite
1.
Mounika Thogaru. Drug related problems on anti-platelets and anti-coagulants in stroke. jpadr [Internet]. 2020Sep.1 [cited 2023Jun.9];1(1):15-8. Available from: https://jpadr.com/index.php/jpadr/article/view/10