Drug Related Problems on Anti-Platelets and Anti-Coagulants in Stroke

Authors: Mounika Thogaru

Abstract

The aim of the research work is to access, evaluate and monitor the drug related problems on antiplatelet and anticoagulants in stroke patients. Antiplatelet agents prevent platelets from dumping and prevent clots from forming and growing. Anticoagulant slowdown clotting thereby reducing fibrin formation and preventing clots. Drug related problems are major concern in the view of physical, psychological and economic burden to patients. In this study 300 numbers of patient were screened including both male and female of all age groups in a super specialty hospital. The numbers of ADRs was found to be predominantly associated with male as compare to female as well as most ADRs reported for patients with cardiac stroke as compared to ischemic stroke and hemorrhagic stroke. Low molecular weight heparins, aspirin, clopidogrel drugs resulted in various adverse drug reactions. Mostly 114 cases of ADR was due to drug-drug interactions followed by drug food interactions and drug ethanol interactions as it was concluded from the study.

Keywords: Heparin; aspirin; clopidogrel; stroke; drug related problems; drug interactions

Article ID: 20201104