A rare case of accelerated gingival overgrowth with high dose amlodipine therapy

Authors: Rakesh B. M., Sharma S.*, Chandana K. H.


Gingival overgrowth represents an over-exuberant response to a variety of local and systemic conditions. Certain anticonvulsants, immunosuppressive drugs, and a number of calcium channel blockers have been shown to produce similar gingival overgrowth in susceptible patients. Among the calcium channel blockers, nifedipine is most frequently associated with gingival overgrowth.  Whereas, there is limited evidence of amlodipine-induced gingival hyperplasia. We report a case of accelerated drug-induced gingival overgrowth in a 60-year-old hypertensive patient taking amlodipine at a dose of 10 mg.

Keywords: Hypertension, calcium channel blockers, drug-induced gingival hyperplasia, adverse drug reaction

Article ID: 20212103