Drug-drug interactions presenting as Bradyarrhythmia and Hyperkalaemia: A Case Report
Abstract
Introduction: Drug-drug interactions can be the major negative consequence while using a multidrug treatment approach. Hypertension is one of the preventable causes of cardiovascular disease. Treatment of hypertension is individualized based on the patient’s condition. Some patients may require simultaneous treatment with 4 to 5 anti-hypertensive drugs.
Case Details: We are presenting a case of a 69-year-old female patient, receiving 4 classes of antihypertensive drugs. Patient was admitted in our hospital with hyperkalemia and bradyarrhythmia. The patient had a history of being treated with Atenolol, Losartan, Hydrochlorothiazide, Diltiazem. Hyperkalaemia observed in this patient can be attributed to Losartan and Atenolol. Bradyarrhythmia can be the result of drug interaction between Diltiazem and Atenolol.
Conclusion: Physician should always keep in mind the interactions and adverse effects caused by medications used in treatment of Hypertension.
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